Page 1 - Reviews - Source Naturals, SAMe, 60 Enteric Coated Tablets (200 mg per Tablet) - iHerb
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Customer Ratings & Reviews

100% authenticOur products are sourced directly from brands or authorized distributors.Show more
4.7
Based on 421 ratings
327
54
30
7
3
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What customers say
Customers have mixed experiences with Source Naturals SAMe. Many users report significant improvements in mood, joint support, and overall well-being. Some mention it helps with seasonal affective disorder, inflammation, and liver health. The product is praised for its quality and effectiveness, often showing results within a few days. However, there are concerns about the dosage size being too low (200mg), requiring multiple doses per day. Some users experienced side effects like irritability or sleep issues when taking higher doses. The packaging received mixed reviews; while some find it convenient, others had issues with pill control. Overall, the supplement is considered beneficial by many but may not be suitable for everyone due to potential side effects.
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KEA-Far North
Posted on Jun 13, 2025
United States
1
0
0
1
Mood stabilizer
Verified purchase
I have found this product spectacular when a little extra hit was needed for mood stabilization. I was encouraged to use it along with my regular regime of L-theanine and ashwagandha. Bonus was that it was going to be helpful for my liver issues! Importantly, this quality product is packaged properly in individual blister packs rather thank in a bottle.
iHerb customer
Posted on Sep 5, 2025
United States
29
0
4
4
Works well
Verified purchase
I am very pleased with this Source Naturals SAM e. I have been taking it for a while now and think it works well to help with mood swings.
iHerb customer
Gold
Posted on Mar 14, 2025
Switzerland
568
0
0
92
High-Quality SAMe for Mood and Joint Support
Verified purchase
I've been using Source Naturals SAMe (200 mg) for a while, and it has noticeably helped with mood stability and joint comfort. The enteric coating ensures good absorption, and I haven’t experienced any stomach discomfort. A reliable option for those looking to support mental well-being and overall health!
iHerb customer
Gold
Posted on Sep 23, 2024
Norway
301
0
0
48
Verified purchase
I've been using SAMe (S-adenosylmethionine) for a little while now, and I'm genuinely impressed. It's known for its mood-boosting and joint-supporting benefits, and I've noticed a positive difference in my overall mood and mental clarity. The capsules are easy to take, and I've experienced no side effects, which is a big plus for me. I appreciate that it also supports liver health, making it a great all-around supplement. If you're seeking something to help with mood support and joint health, I highly recommend giving SAMe a try!
iHerb customer
Posted on Jun 26, 2024
Canada
521
0
5
159
Прекрасно!
Verified purchase
Same Pills, which contain S-adenosylmethionine, have been known to support mood balance and joint health. I found them effective in boosting my overall mood and energy levels. Within a few weeks of consistent use, I noticed a significant improvement in my emotional well-being and felt more resilient to daily stressors.
iHerb customer
Posted on Feb 19, 2024
United States
5
0
0
1
Excellent SAMe product
Verified purchase
Source Naturals SAMe has helped me by improving my mood and reducing inflammation. SAMe is not for everyone, because there is a risk of mania for a small subset of individuals. I would work with an MD or ND if using it. Source Naturals has a great reputation for quality.
iHerb customer
Gold
Posted on Apr 26, 2026
United States
366
0
3
93
Good brand for SAM-e
Verified purchase
To learn more about it use go here 5 Science-Backed SAMe Benefits, According To A Naturopathic Doctor https://www.iherb.com/blog/sam-e-health-benefits/1901?gad_campaignid=1627364330&gad_source=1
iHerb customer
Posted on Mar 1, 2026
United States
1
0
1
0
Joint pain relief
Verified purchase
In stores they put Sam-e by “mood” supplements. This actually is for joint pin relief and it works! Just need to take it daily and give it a week or so.
iHerb customer
Gold
Posted on Jan 30, 2026
Singapore
423
0
0
116
this brand has the history and quality
Verified purchase
as SAM0e at 400mg some time cud have over methylation. i used it not for moods but to clear the histamine in my system. i prefer luteolin better
iHerb customer
Silver
Posted on Oct 25, 2025
Australia
109
0
7
18
methylation
Verified purchase
SAMe is essential for me, along with Niacin it helps control my anxiety and has done for the past 10 years